SporeWill Wright has been developing a game called Spore for a while. The basics of it are that you, the player, start out as a measly bacteria, and over time evolve into something much greater, from a new animal in the sea, to one on land, to one that begins a social heirearchy, all the way to a civilization which can propel itself off world, exploring new plantes, and eventually other galaxies.
Sound awesome? Check out this video. It's a bit long, but you can skip around. It was shown at the GDC way back in January I think, or was it like August? I think it's August. Long time ago, but I just discovered this video now, and I was amazed enough to share it here on the site. Looks to provide far more creativity and entertainment then his already acclaimed Sims series.
It's about a half hour long, so just skip around a bit if you have too.